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A comparative pharmacological investigation of Ashwagandha and
Ginseng.
Grandhi A, Mujumdar AM, Patwardhan B.
Indian Drugs Research
Association, Pune.
The aqueous suspensions of roots of an
Indian drug Ashwagandha and the Korean drug Ginseng were tested
comparatively for 2 pharmacological activities, namely the
anti-stress activity by the 'mice swimming endurance test' and
anabolic activity by noting gain in body weights and levator ani
muscle in rats. A significant increase in mice swimming time was
shown by Ginseng (P < 0.001) and Ashwagandha (P < 0.01) as compared
to the control group. Significant increase in body weights in the
Ashwagandha treated group (P < 0.05) was better than Ginseng (P <
0.5). Gain in wet weights of the levator ani muscle were also
significant in Ginseng (P < 0.001) and Ashwagandha (P < 0.01)
treated groups, however, the weight gain of dried levator ani
muscles showed comparable results for both these drugs (P < 0.01).
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